Abstract: Medical educators at home and abroad have done a lot of exploration and practice in reforming medical teaching based on organ system, and achieved certain results. However, in the process of promoting clinical teaching, this reform has encountered an insurmountable constraint factor, that is the asymmetry between the setting of clinical departments and the clinical teaching curriculum based on organ system. This article starts from the bottleneck problem of organ system teaching reform, and tries to explore a complete reform route based on organ system from clinical departments to clinical courses. Relying on Luhe Clinical Medical College, Capital Medical University, the pilot project will break the original clinical department system and clinical curriculum system, and establish 24 clinical centers, 4 clinical medical technology centers, and 4 clinical education centers, forming a new department organizational system, further promoting the education and teaching reform centered on organ system on this basis, and providing beneficial exploration for improving the ability of clinical medical talents.

Key words: organ system, disease as the core, reform in education, clinical medicine, talent training, mode