Abstract: Objective  To explore the application of clinical research training combined with problem-based learning (PBL) in clinical probation teaching of otorhinolaryngology. Methods  Following the order of probation time, clinical students in Sun Yat-sen University were randomly divided into the experimental group and the control group. The experimental group adopted clinical research training combined with PBL, and the control group adopted PBL teaching method. This study analyzes the differences between both groups in terms of test scores and their evaluation including improving their study interests, training their clinical research literacy, improving their clinical thinking ability, enriching their probation information, and enhancing their confidence in future clinical work. Results  There were significant differences between the two groups (P<0.05). The questionnaire survey shows that the satisfaction rate of the experimental group is 83.1%; the evaluation of the experimental group is better than that of the control group in terms of improving their study interests, training their clinical research literacy, improving their clinical thinking ability, enriching their probation information, enhancing their confidence in future clinical work, and satisfaction rate of the teaching method (P<0.05). The total of 81.7% of the experimental group are confident to carry out clinical research in the future. Conclusion  PBL combined with clinical scientific research training can be applied to clinical probation teaching of otorhinolaryngology, is proved beneficial to cultivate students clinical scientific research thinking, improve students clinical thinking ability and effectively improve the teaching quality.

Key words: clinical research literacy,  , problem-based learning teaching method, clinical probation teaching of otorhinolaryngology