Abstract: Objective　To conduct an in-depth analysis of the achievements and challenges in the homogenization construction of multi-campus public hospitals, and promote their high-quality and coordinated development.Methods　The structure-process-outcome model was adpoted in this study to analyze the multi-campus development of Beijing Friendship Hospital, Capital Medical University from various perspectives. The evaluation was performed in the aspects of homogeneous provision of medical services, optimization of human resources, information interconnectivity, enhancement of disciplinary influence, deepening of cultural development, etc. Simultaneously, the key directions requiring further exploration in current practice were identified.Results　The hospital adopted an integrated horizontal and vertical matrix management structure across its multiple campuses, implemented a dynamic staff rotation system, promoted integrated bed management and equipment sharing mechanisms, established a unified medical quality and safety system across all campuses, created an efficient information exchange platform, and maintained a parallel advancement of disciplinary specialization and collaboration, consolidating synergistic efforts across the entire institution. From May 2024 to April 2025, there were no statistically significant differences in the mortality rate of inpatients (P=0.578), the incidence of hospital-acquired pressure ulcers (P=0.671), the rate of Class I surgical incision infections (P=1.000), medical record compliance rate (P=1.000), and the incidence of medical disputes (P=0.195) across the three campuses. However, there were differences in indicators such as the rates of Class III and IV surgeries, average length of stay, and case mix index (CMI).Conclusion　The hospital has laid solid foundations for efficient homogenization construction through its integrated management model and matrix structure. While initial success has been achieved in the homogenization of hospital operation, discrepancies remain in indicators such as the rates of Class III and IV surgeries and the CMI. These issues may be attributed to factors such as changes in the disease spectrum resulting from the differentiated development of disciplines across different campuses. A scientific and authoritative evaluation framework should be systematically established for multi-campus homogenization development, thereby providing a scientific basis for the transition from physical expansion to substantive homogenization across these campuses.

Key words:  , multi-campus｜ homogenization｜ SPO model｜ public hospital｜matrix management system｜high-quality development｜ coordinated development