Abstract: Objective　To reform and innovate the teaching method of Traditional Chinese Medicine treatment based on syndrome differentiation in clinical medicine specialty of medical colleges.Methods　This study integrated teaching content, cultivated new teacher team, and integrated "Internet +" into teaching practice. We also adopted "online" and "offline" blended teaching method, combined theory with practice, focused on raising questions, analyzing problems and solving problems, reformed the assessment methods and evaluation standards, and incorporated random classroom Q&As, course presentations, recitation of theoretical knowledge and other daily performance as well as clinical probation assessment into the course scores.Results　Two rounds of teaching practice proved that the method not only significantly improved the teaching performance of syndrome differentiation and treatment course, but also greatly improved the students' perception, understanding and practical application ability of the knowledge of syndrome differentiation and treatment of Traditional Chinese Medicine. Conclusion  In view of the existing problems in the teaching of Traditional Chinese Medicine in medical colleges and universities, it is conducive to improving the teaching quality by actively reforming the teaching mode.

Key words: medicine college, Traditional Chinese Medicine syndrome differentiation and treatment, problem, countermeasures