Abstract: In order to cultivate the application-oriented talents suitable to the needs of the pharmaceutical market, the college of pharmacy of Qilu Medical University has explored and practiced the talent training mode. College, especially major in pharmacy in the platform of university-enterprise cooperation, has investigated the demand for the enterprises and searched the position for undergraduate students, combining with the characteristics and development of pharmaceutical industry. It is the key that lies in the undergraduate application training, based on the previous reform. Meantime, the purpose is to explore the constructing university-enterprise cooperation and industry-university-research application talents training mode.