Abstract: According to the characteristics of organic chemistry experiment, the main safety problems in the teaching of organic chemistry experiment are analyzed. This paper expounds the contents and methods of the training of undergraduates' safety quality in the course of organic chemistry experiment teaching. Some practices and experiences in the teaching of organic chemistry experiment in our university are listed, and network learning system of safety education will be constructed in the future, which is advantageous to improve the information level of the laboratory safety management, and it is also beneficial to improve the safety quality of the undergraduates.