Abstract: The significance and disciplinary status of clinical pharmacokinetics in drug development and clinical applications are undeniable, forming a crucial theoretical basis for drug bioequivalence study. However, traditional experimental teaching methods, challenged by resource limitations and ethical concerns, fail to meet the educational demands of the new era. This article employs virtual experiment technologies, using the simulation of the bioequivalence evaluation of Dabigatran Etexilate Capsules as a case study, to design a series of instructional experiments. These include the design of bioequivalence trials, calculation of pharmacokinetic parameters, methodological validation, and bioequivalence assessment, exploring the application and effectiveness of virtual experiments in clinical pharmacokinetics experimental teaching. Integrating teacher evaluations, peer assessments, experimental reports, final grades, and survey results, it is demonstrated that virtual drug bioequivalence evaluation trials can stimulate students' interest in learning, enhance their practical skills, and improve their scientific abilities. The application of virtual drug bioequivalence evaluation technology significantly enhances the teaching outcomes in pharmacokinetics and enriches the students' learning experience. This technology not only addresses the resource and ethical issues present in traditional experimental teaching but also provides new approaches and methods for clinical pharmacy education. Furthermore, it aids in cultivating high-quality professionals who meet the demands of modern drug development, thereby advancing clinical pharmacy education.

Key words: virtual experiment, drug bioequivalence study, clinical pharmacy, pharmacokinetics