Abstract: The problem-based learning is called PBL teaching. It is a student-centered teaching, in which teachers play a leading role in using typical cases of clinical disease to demonsrate the disease’s nodes and process. The four concrete measures include cases collection, teachers’ training, students guidance, and preparation of basic conditions. The teaching consists of seven steps: analyzing clinical cases, explaining questions, discussing points, integrating issues, summary and conclusions. This teaching enables students to acquire knowledge points in the chapter, and improve their thinking in diagnosis and treatment.