Abstract: As the basic content of personnel management in all enterprises and institutions, , personnel file management covers personal identity, qualifications, work experience, and other related contents. It is an important record of personal growth and development. It plays an important role in job classification, social security and so on. In the era of rapid development of the current information technology, informationization construction for personnel file management has become a general trend. With the computer and internet applications, we can get rid of the inefficient limitations of the former paper files management, such as store, transfer and file service etc. Instead, we should adapt to the practical demand of current times, promote information technology application in personnel file management for the relevant industry and improve the effectiveness of the reform. This article discusses the informationization construction of hospital personnel records management under the new situation so as to provide a relevant reference.