Abstract: This study is based on the construction and application of brainstorming and innovative case teaching methods in the teaching practice of critical illness medicine, and proves that the brainstorming teaching can greatly improve students’enthusiasm and give full play to their independent initiatives. Innovative case teaching method critical medical courses can cultivate students’ problem-solvingability. The combination of the two methods can help students combine theory with practice, strengthen students’ ability of independent learning and independent thinking, and thus greatly improve the teaching quality.