Abstract: "Overall scheme to coordinated promote the construction of world-class universities and disciplines" is a recently-launched public education policy to promote China’s construction of the powerful country in higher education groups of high-level universities and disciplines will be raised up to the world-class level. This article selected a local medical university showed good development momentum in recent years, analyzed the national key disciplines construction condition, according to the policy construction goal and value orientation, put forward some thinking and suggestions to promote world-class discipline construction based on the key discipline construction in local medical university.