Abstract: TBL of Learning-Research-Teaching synergy is a team-based teaching method which is to develop students’ self-study capabilities. The research applied this method to 4-year Medical Imaging Technique Major students, understood the students’ attitudes and gains by adopting questionnaire survey and interview, and explore the effect and significance of this teaching method. Analysis showed that TBL can effectively improve students' self-study capability and team work spirit. In addition, it can help to train the students’ fundamental scientific research qualities.