Abstract: Cultivating excellent medical talents is not only an urgent need to deepen the reform of medical and health system and to promote the development of health services, but also an important mission for medical college. In order to meet the internal and external requirements, and reach a target in both short and long terms, we probed deeply into the basic connotation of five-year excellent medical talent training in the local college, and established the framework of path construction from the target orientation, curriculum system, teaching methods, security conditions, construction of study style and other aspects.